MICRODELETION SYNDROMES
REMBRANDT® Prader-Willi/Angelman Syndrome (PWS/AS)
Technology | FISH | ISH |
| Application | Microdeletion syndrome | Microdeletion syndrome |
| Area of interest | Fixed cytological specimen | Fixed cytological specimen |
| Region | 15p11.1-q11.1 and 15q11.2 | 15p11.1-q11.1 and 15q11.2 |
| Label | ♦ (AF488, 2000) and ♦(AF555, 3000) | Biotin (0100) and Digoxigenin (9900) |
| Product No. | C804K.2030.05 | C804K.0199.05 |
| C804K.2030.10 | C804K.0199.10 | |
| Product Type | In vitro diagnostics (IVD) or Research use only (RUO) | Research use only (RUO) |
| Intended use | The REMBRANDT® Prader-Willi/Angelman syndrome (PWS/AS) FISH detection assay is able to detect a deletion in the PWS/AS critical region 15q11.2, in comparison to the centromeric region of the human chromosome 15, by means of direct in situ hybridization | The Rembrandt® LSI 15q11.2/CEP15-ISH detection assay is intended to detect the 15q11.2 locus, in comparison to the centromeric region of chromosome 15. |
| Kit contents | C804P.2030 LSI 15q11.2/CEP15-FISH probe mix | C804P.0199 LSI 15q11.2/CEP15-ISH probe mix |
| R018R.0000 Pepsin diluent | R018R.0000 Pepsin diluent | |
| R011R.0000 Pepsin powder | R011R.0000 Pepsin powder | |
| R025R.0000 PanWash 4, 25x SSC | R025R.0000 PanWash 4, 25x SSC | |
| Z000R.0050 Fluorescent mounting medium | ||
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All products are also available as stand-alone RUO products